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Metabolism: Oxycodone hydrochloride is extensively metabolized to noroxycodone, oxymorphone, as well as their glucuronides. The major circulating metabolite is noroxycodone with an AUC ratio of 0.To protect against extreme exposure to OXYCONTIN by younger kids, recommend caregivers to strictly adhere to advised OXYCONTIN dosing.Will not abruptly di